Free Ebook Hematopoietic Stem Cell Biology (Stem Cell Biology and Regenerative Medicine)
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Book Details :
Published on: 2009-12-04
Released on: 2009-12-04
Original language:
In the summer of 1988, my developmental biology professor announced to the class that hematopoietic stem cells (HSCs) had finally been purified. Somehow, I never forgot the professor’s words. When I started working in Dr. Irv Weissman’s labo- tory at Stanford as a postdoctoral fellow, I realized that the findings mentioned by the professor were from Weissman’s laboratory and had been published in a 1988 edition of the journal Science. It has been over 20 years since the publication of that seminal paper, and since then tremendous advances in understanding the biology and maturation of HSCs, namely the process of hematopoiesis, which includes lymphocyte development, have been made. These discoveries were made possible in part by advancements in technology. For example, recent availability of user friendly fluorescence activated cell sorting (FACS) machines and monoclonal an- bodies with a variety of fluorescent labels has allowed more scientists to sort and analyze rare populations in the bone marrow, such as HSCs. All classes of hematopoietic cells are derived from HSCs. Stem cell biology draws enormous attention not only from scientists, but also from ordinary people because of the tremendous potential for development of new therapeutic application to diseases that currently lack any type of effective therapy. Thus, this type of “regenerative medicine” is a relatively new and attractive field in both basic science and clinical medicine. Stem cell - Wikipedia Transmission electron micrograph of an adult stem cell displaying typical ultrastructural characteristics. Stem Cell Research - Stem Cell Treatments - Treatments ... Stem cells can grow into any one of the body's more than 200 cell types. Stem cells assist the body in repairing cells damaged by disease injury and everyday life. Allogeneic Hematopoietic Stem-Cell Transplantation for ... Background Myeloablative allogeneic hematopoietic stem-cell transplantation is curative in children with sickle cell disease but in adults the procedure is unduly toxic. Childhood Hematopoietic Cell Transplantation (PDQ)Health ... The higher chemotherapy/radiation therapy dose that can be used because of hematopoietic stem cell support achieves a significantly higher cell kill of the disease. Stem Cell Assays Reproducible Research on Stem Cells Cells Weekly is a digest of the most interesting news and events in stem cell research cell therapy and regenerative medicine. Cells Weekly is posted every Sunday night! All Things Stem Cell Visual Stem Cell Glossary Adult stem cells (or Somatic Stem Cell): Stem cells that are harvested from tissues in an adult body. These cells are usually multipotent meaning they can ... Issue: Stem Cell Reports x In this article Han and colleagues investigate the role of hippocalcin in neuronal differentiation of neural stem cells. They show that hippocalcin promotes ... Home: Cell Stem Cell Cell Stem Cell publishes peer-reviewed articles reporting findings of unusual significance in all areas of stem cell research including biological advances and ... Shripad Banavali-Hematopoietic Stem Cell Transplantation ... Hematopoietic Stem Cell Transplantation: Need for Research & Potential Applications. Its status in India Shripad D. Banavali* (PASRM** 2009-002) Stem-cell therapy - Wikipedia Stem-cell therapy is the use of stem cells to treat or prevent a disease or condition. Bone marrow transplant is the most widely used stem-cell therapy but some ...
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